Substance Use Treatment in San Francisco, CA

Epiphany Residential

What Does Epiphany Residential Offer?

Epiphany Residential is a substance use treatment facility at 100 Masonic Avenue, San Francisco, California, offering residential treatment. It accepts Medicaid, Medicare and state-financed insurance and offers a sliding fee scale. Medication treatment: naltrexone.

Reviewed by Michael Rupe ·October 2, 2026

100 Masonic Avenue
San Francisco, CA 94118

Listed in SAMHSA's FindTreatment.gov, checked October 2026. A listing is not an endorsement. Call to confirm services, openings and costs before you go.

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Treatment facility (SAMHSA listing)This facility

Types of Care at Epiphany Residential

Residential/24-hour residential
Long-term residential
Short-term residential

Payment, Insurance and Help Paying

Federal, or any government funding for substance use treatment programs
Medicare
Medicaid
State-financed health insurance plan other than Medicaid
Sliding fee scale (fee is based on income and other factors)

Medication Treatment

Accepts clients using MAT but prescribed elsewhere
Buprenorphine with naloxone
Buprenorphine without naloxone
Naltrexone (oral)
Naltrexone (extended-release, injectable)

Who the Program Serves

Adult women
Pregnant/postpartum women
Clients with co-occurring mental and substance use disorders
Clients who have experienced trauma
Ages: Young Adults
Ages: Adults
Ages: Seniors
Accepts: Female

Language Services

Sign language services for the deaf and hard of hearing

Licensing and Accreditation

State substance use treatment agency
State department of health

Treatment Approaches

Anger management
Brief intervention
Cognitive behavioral therapy
Contingency management/motivational incentives
Community reinforcement plus vouchers
Motivational interviewing
Relapse prevention
Substance use disorder counseling
Trauma-related counseling
Telemedicine/telehealth therapy
12-step facilitation

Assessment, Recovery Support and Other Services

Comprehensive mental health assessment
Comprehensive substance use assessment
Outreach to persons in the community
Complete medical history/physical exam
Screening for tobacco use
Screening for substance use
Screening for mental disorders
Aftercare/continuing care
Discharge Planning
Naloxone and overdose education
Outcome follow-up after discharge
Self-help groups
Housing services
Assistance with obtaining social services
Recovery coach
Mentoring/peer support
Employment counseling or training
Acupuncture
Residential beds for clients' children
Case management service
Child care for clients' children
Domestic violence services, including family or partner
Early intervention for HIV
Mental health services
Social skills development
Transportation assistance
Integrated primary care services
Suicide prevention services
Breathalyzer or blood alcohol testing
Drug or alcohol urine screening
TB screening

Before you commit, confirm openings, costs and the program's state license. How to choose a rehab you can trust lists the questions to ask when you call, and addiction treatment in California lists the state's treatment agency.