Substance Use Treatment in Hannibal, MO

Mark Twain Behavioral Health, 146 Communications Drive

What Does Mark Twain Behavioral Health, 146 Communications Drive Offer?

Mark Twain Behavioral Health, 146 Communications Drive is a substance use treatment facility at 146 Communications Drive, Hannibal, Missouri, offering detox, residential treatment, partial hospitalization, intensive outpatient and outpatient treatment. It accepts Medicaid, private insurance and self-pay. Medication treatment: buprenorphine and naltrexone.

Reviewed by Michael Rupe ·October 2, 2026

146 Communications Drive
Hannibal, MO 63401

Listed in SAMHSA's FindTreatment.gov, checked October 2026. A listing is not an endorsement. Call to confirm services, openings and costs before you go.

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Treatment facility (SAMHSA listing)This facility

Types of Care at Mark Twain Behavioral Health, 146 Communications Drive

Outpatient
Residential/24-hour residential
Outpatient detoxification
Outpatient day treatment or partial hospitalization
Intensive outpatient treatment
Outpatient methadone/buprenorphine or naltrexone treatment
Regular outpatient treatment
Residential detoxification
Short-term residential

Payment, Insurance and Help Paying

Federal, or any government funding for substance use treatment programs
Medicaid
Private health insurance
Cash or self-payment
SAMHSA funding/block grants

Medication Treatment

Buprenorphine maintenance
Prescribes buprenorphine
Prescribes naltrexone
Relapse prevention with naltrexone
Accepts clients using MAT but prescribed elsewhere
Lofexidine or Clonidine detoxification
Acamprosate (Campral®)
Disulfiram
Buprenorphine with naloxone
Buprenorphine without naloxone
Naltrexone (oral)
Naltrexone (extended-release, injectable)
Clonidine

Detox Services

Alcohol Detoxification
Benzodiazepines Detoxification
Cocaine Detoxification
Methamphetamines detoxification
Opioids detoxification

Who the Program Serves

Adult women
Adult men
Criminal justice (other than DUI/DWI)/Forensic clients
Ages: Young Adults
Ages: Adults
Ages: Seniors
Accepts: Female
Accepts: Male
Specially designed program for DUI/DWI clients

Licensing and Accreditation

State mental health department
Commission on Accreditation of Rehabilitation Facilities (CARF)

Treatment Approaches

Anger management
Brief intervention
Cognitive behavioral therapy
Motivational interviewing
Relapse prevention
Substance use disorder counseling
Trauma-related counseling
Telemedicine/telehealth therapy
12-step facilitation

Assessment, Recovery Support and Other Services

Comprehensive substance use assessment
Interim services for clients
Outreach to persons in the community
Screening for tobacco use
Screening for substance use
Screening for mental disorders
Professional interventionist/educational consultant
Aftercare/continuing care
Discharge Planning
Naloxone and overdose education
Outcome follow-up after discharge
Self-help groups
Housing services
Assistance with obtaining social services
Mentoring/peer support
Case management service
Social skills development
Transportation assistance
Suicide prevention services
Breathalyzer or blood alcohol testing
Drug or alcohol urine screening

Before you commit, confirm openings, costs and the program's state license. How to choose a rehab you can trust lists the questions to ask when you call, and addiction treatment in Missouri lists the state's treatment agency.