Substance Use Treatment in Harrisburg, PA

Genesis House Inc

What Does Genesis House Inc Offer?

Genesis House Inc is a substance use treatment facility at 121 Locust Street, 2nd and 3rd Floor, Harrisburg, Pennsylvania, offering intensive outpatient and outpatient treatment. It accepts Medicaid, private insurance, state-financed insurance and self-pay.

Reviewed by Michael Rupe ·October 2, 2026

121 Locust Street, 2nd and 3rd Floor
Harrisburg, PA 17110

Listed in SAMHSA's FindTreatment.gov, checked October 2026. A listing is not an endorsement. Call to confirm services, openings and costs before you go.

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Treatment facility (SAMHSA listing)This facility

Types of Care at Genesis House Inc

Outpatient
Intensive outpatient treatment
Regular outpatient treatment

Payment, Insurance and Help Paying

Federal, or any government funding for substance use treatment programs
Medicaid
Private health insurance
Cash or self-payment
State-financed health insurance plan other than Medicaid
SAMHSA funding/block grants

Medication Treatment

Accepts clients using MAT but prescribed elsewhere

Who the Program Serves

Adolescents
Young adults
Adult women
Pregnant/postpartum women
Adult men
Seniors or older adults
Veterans
Active duty military
Members of military families
Criminal justice (other than DUI/DWI)/Forensic clients
Clients with co-occurring mental and substance use disorders
Clients with co-occurring pain and substance use disorders
Clients with HIV or AIDS
Clients who have experienced sexual abuse
Clients who have experienced intimate partner violence, domestic violence
Clients who have experienced trauma
Ages: Children/Adolescents
Ages: Young Adults
Ages: Adults
Ages: Seniors
Accepts: Female
Accepts: Male
Specially designed program for DUI/DWI clients

Language Services

Spanish
Sign language services for the deaf and hard of hearing
American Indian or Alaska Native languages
Other languages (excluding Spanish)
Any Chinese Language
Arabic
Creole
Farsi
French
German
Greek
Hebrew
Hindi
Hmong
Italian
Japanese
Korean
Ojibwa
Polish
Portuguese
Russian
Tagalog
Vietnamese
Yupik

Treatment Approaches

Cognitive behavioral therapy
Motivational interviewing
Matrix Model
Relapse prevention
Substance use disorder counseling
Trauma-related counseling

Assessment, Recovery Support and Other Services

Comprehensive substance use assessment
Screening for tobacco use
Screening for substance use
Aftercare/continuing care
Discharge Planning
Outcome follow-up after discharge
Mentoring/peer support
Social skills development
Treatment for gambling disorder
Treatment for other addiction disorder

Before you commit, confirm openings, costs and the program's state license. How to choose a rehab you can trust lists the questions to ask when you call, and addiction treatment in Pennsylvania lists the state's treatment agency.